Posts by Ben
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1) Message boards : News : GridRepublic (Message 2837)
Posted 7 Dec 2016 by Profile Ben
Message from Ant.
Dear all,
I mentioned many months ago - some time in early 2015 - that GridRepublic in Boston offered to take over the server management of FiND@H.
It was - and still is - my intention to make results from the FiND@H project publically available. I've built a website that displays the first results - http://chemware.ucd.ie/FiNDaH/.
The idea is that anyone, anywhere, has access to this data and can validate the results in the lab.

That's where things get tricky. If an academic lab - or for that matter a biotech company - puts their own time and money into validating these data, then they get the patents and profit. Ideally government money should pay for these validation studies - socialising the profits - but as I am in Ireland and computational drug discovery is off the bottom of the priority list, I repeatedly failed to get funding for the validation studies from the HRB, SFI and EI research funding agencies.

I am now no longer employed to be a research scientist and have been forced to take an admin role at a college to break out of the annual contract life of postdocs. Hence the project went dormant until GR picked it up again.

But I still want the results validated in the lab. I repeatedly tried to get funding from the Gates foundation, but ironically they refused to fund projects that where computational. I tried croudfunding, and the generous donations we received covered the cost of new hard drives - a far cry from the 100,000s needed to support lab validation studies.

So I'm still hopeful that some angel investor will swoop in and offer to validate the work. Will the profits be shared? - no. My contract with the FiND@H volunteers ends with porting the data onto the web. Now anyone in the world with deep pockets can take advantage of the data. The risk is still high and there is no final guarantee. Of course I hope I'm right, and that this project works. But the person who puts hard cash down to validate the data is the one who walks away with the spoils. At the moment this could be a lab/company in India or South Africa or wherever... for all I know.

I'm just delighted that GridRepublic have offered to keep the project alive... I think we could use this method for all sorts of infectious diseases, given the chance. In the end I hope someone, somewhere, puts in the effort to validate the data in vitro.

Ciao,
Ant

Ps: I have not heard of any BOINC project socialising the profits from the computation work. For instance, the WCG project similar to ours - Go Fight Malaria At Home - also put all their data online. I have no idea if this has been validated in house by them - then they could hold patents on good results and license to large pharma and (potentially) make profits from it. I have no idea... just saying. The nett result of this work are possible hypothetical interactions, which will take a lot of time and money to validate.


Also, look here -> https://boinc.berkeley.edu/dev/forum_thread.php?id=11309
2) Message boards : Number crunching : NO new work. (Message 2746)
Posted 8 Nov 2016 by Profile Ben
I've no idea. I can share the database with the new project when it comes up, but I have no idea when. I might be in an other country with no access to UCD network when the project will go live.
3) Message boards : Number crunching : NO new work. (Message 2734)
Posted 24 Aug 2016 by Profile Ben
It's better to remove the project :)

We currently have nothing to crunch. I know that Ant is speaking with GridRepublic about restarting the project with new server, new data, new staff but I've no idea when this is coming.
4) Message boards : Number crunching : NO new work. (Message 2732)
Posted 24 Aug 2016 by Profile Ben
It's maybe because I stopped the BOINC server. You want me to try to restart it?
5) Message boards : Number crunching : SSL Certificate (Message 2730)
Posted 16 Aug 2016 by Profile Ben
Hi :)

The project is currently not running and we are going to move it to another server (TBA).

There is no harm if you remove it from the whitelist as we currently have nothing to crunch.
6) Message boards : News : Database change (Message 2692)
Posted 29 Jan 2016 by Profile Ben
Database server changed.
7) Message boards : News : Database change (Message 2691)
Posted 26 Jan 2016 by Profile Ben
No, there is no more WUs for now.

I'm still maintaining the server in case, but for now the project is on sleeping mode.
8) Questions and Answers : Wish list : FiND@Home for Android Lollipop (Message 2688)
Posted 15 Jan 2016 by Profile Ben
The Zenfone is a really good phone, I have the Zenfone 2.

The project is dry of work and I have no idea when we are going to put more tasks.
9) Message boards : News : Database change (Message 2687)
Posted 13 Jan 2016 by Profile Ben
Hi,

If the website stop working suddenly it's because I'm moving the database to a new server.

But I've no idea when.

:)
10) Message boards : Number crunching : NO new work. (Message 2670)
Posted 21 Nov 2015 by Profile Ben
Do I have an RSS feed?

:D

Didn't know...
11) Message boards : Number crunching : NO new work. (Message 2666)
Posted 12 Nov 2015 by Profile Ben
I'm going to post a message soon. I don't have any new work for now. I might have some spare WUs (the failed/bugged ones).

More info coming Soon(TM)
12) Message boards : Science : FightMalaria@Home Source Code (Message 2664)
Posted 6 Nov 2015 by Profile Ben
That was before I came here and rewrite the code.

Source available on my Github.
https://github.com/oXis/bin_boinc
13) Message boards : Number crunching : NO new work. (Message 2662)
Posted 4 Nov 2015 by Profile Ben
The project is dry.

I need some time to look at the data. I will probably redo some failed tasks.
14) Message boards : Number crunching : NO new work. (Message 2658)
Posted 29 Oct 2015 by Profile Ben
2,484,516 new WUs and then... done :)

I'll post a message later about what's next.
15) Message boards : News : Kernel panic (Message 2648)
Posted 27 Oct 2015 by Profile Ben
The BOINC database, the one which stores the WUs, the Users, the forum, etc. crashed. But I wasn't sysamdin on this server.

We rebooted the server and I'm now going to have rights on it.
16) Message boards : Number crunching : NO new work. (Message 2640)
Posted 19 Oct 2015 by Profile Ben
Still some millions to go. I'm putting 4M WUs :)

Edit: 2,484,516 WUs still in my queue.
17) Message boards : Cafe : L'Alliance Francophone recruit post (Message 2632)
Posted 13 Oct 2015 by Profile Ben
Je passe dire bonjour à mes compatriotes.

Le projet tourne toujours mais sans trop de nouveauté car je suis en train de me faire bouffer par ma thèse...

Merci de participer au projet :)
18) Message boards : Science : Nobel Prize 2015 in medicine (Message 2627)
Posted 6 Oct 2015 by Profile Ben
"discoveries concerning a novel therapy against Malaria"


We are working on that :)
19) Message boards : Number crunching : GPU (NVidia) WUs... in the foreseeable future? (Message 2619)
Posted 5 Oct 2015 by Profile Ben
I like the very :)

I deactivated the multi-CPU, because Vina takes everything it can get.
20) Message boards : News : 57,634,517 WUs (Message 2616)
Posted 1 Oct 2015 by Profile Ben
You went through 40M over 57M WUs.


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